Melissa Villars, MD, MPH

The ICU-ROX study, designed as the largest RCT of mechanically ventilated ICU patients, investigates whether conservative oxygen therapy could reduce mortality. Are the results enough to tip the scale
This review article was trying to take another look at the impact of epinephrine, especially its impact on meaningful neurologic survival, to see if the debates launched by the PARAMEDIC-2 trial were
Can vitamin C benefit patients with sepsis-related ARDS? Take a look at the evidence from the CITRIS-ALI study before you take a stance in this ongoing debate.
Sometimes a clinical trial shows no statistical differences yet can help to illuminate best practices. Count the ESETT Trial as one of them.
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