Browsing: Toxicology

At toxic doses, tricyclic antidepressants (TCAs) cause blockade of sodium channels, muscarinic receptors, and alpha-adrenergic receptors. Slowed ventricular contraction, tachycardia, and vasodilation
Emergency physicians have watched with excitement the rapid development of COVID-19 vaccines. However, while we were watching the rapid scientific development, there was a concurrent wave of misguided
Initially marketed as an atypical antidepressant for adults, bupropion gained popularity for its use in tobacco cessation and for its lack of sexual side effects commonly seen with other typical antid
Climate health and public health are linked in ways that become more obvious every year. In this context, we will summarize the marine toxins that are sending more patients to the emergency department
Second-generation antipsychotics are becoming more commonly used because of their safety profiles. Nevertheless, this case demonstrates a risk of QTc prolongation and torsades de pointes with olanzapi
Acetaminophen toxicity is one of the most common causes of liver toxicity in the United States. New data reveals that fomepizole may be hepatoprotective in high dose acetaminophen toxicity when review
Acquired methemoglobinemia, a pathologic condition due to elevated quantities of methemoglobin in the blood, is an infrequent presentation in a healthy adult patient. This case illustrates the risk as
Erythema multiforme is an acute skin disorder. While most cases are the result of an infection, the condition can also result from autoimmune disorders, malignancy, and drug use.
Doxepin is a tricyclic antidepressant (TCA) that was primarily approved for depression but has also been approved by the Food and Drug Administration (FDA) to treat insomnia and anxiety. Do you know h
SGLT-2 inhibits can cause massive osmotic diuresis and intravascular volume depletion. The body’s appropriate response to this is production of antidiuretic hormone, an excess of which is capable of c