Critical Care Alert , Critical Care , Cardiology

Critical Care Alert: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial

1/15/2026 Jacqueline Zhu, MD , Joshua Novy, MD, MBA, MS , Alex Lucas, MD

Following an initial 2019 study, the ANDROMEDA-SHOCK-2 Trial looks at outcomes when applying a personalized hemodynamic resuscitation strategy for critically ill patients. This Critical Care Alert cha

Critical Care , Critical Care Alert

Critical Care Alert: Targeted Temperature Management for Cardiac Arrest with Non-shockable Rhythm - The HYPERION Trial

12/19/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD

Moderate therapeutic hypothermia could be another tool in treating cardiac arrest patients. But how much should a patient be cooled? The HYPERION Trial doesn't resolve that debate.

Critical Care , Cardiology , Deep Dive in CritCare

Deep Dive into the Evidence: Cardiac Ultrasound in Cardiac Arrest

9/5/2019 Sean M. Hickey, MD , Bryan Beattie, MD , Susannah Empson, MD , Mina Ghobrial, MD , Jaskirat Gill, MD , Emily Gillespie , Meghan Gorski, DO , Omid Manoochehri, MD , Joshua Novy, MD, MBA, MS , Jonathan Pickos, DO , Mark Ramzy, DO, EMT-P , Yanika Wolfe, MD

Will transesophageal echocardiography become the first imaging incorporated into ACLS protocols?

Critical Care , Critical Care Alert

Critical Care Alert: The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS)

8/12/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD

Fluid resuscitation guidelines for severe sepsis and septic shock presently address only the initial phase of resuscitation. The RIFTS trial examines the efficacy of a restrictive IV fluid resuscitati

Critical Care , Critical Care Alert

Critical Care Alert: Re-evaluation of Systemic Early Neuromuscular Blockade: The ROSE Trial

7/16/2019 Jonathan Pickos, DO , Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD

Does early neuromuscular blockade accompanied by heavy sedation in ARDS cases improve all-cause in-hospital mortality rates? The ROSE trial investigates.

Critical Care , Critical Care Alert

Critical Care Alert: Coronary Angiography after Cardiac Arrest without ST-Segment Elevation

5/17/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD

This study examines whether immediate coronary angiography in the setting of ROSC without STEMI changes on ECG following out of hospital cardiac arrest confers superiority in 90 day mortality compared