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Rita A. Manfredi, MD, FACEP

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Professor of Clinical Emergency Medicine
Department of Emergency Medicine
Hospice and Palliative Medicine
The George Washington University School of Medicine

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Pain Management

Effective and Safe Opioid Dosing for Opioid-Tolerant Patients in the ED

9/10/2023 Alexander Steele, MD , Leonie Oostrom-Shah, MD , Brian Gacioch, MD, FACEP, FAAEM , Rita A. Manfredi, MD, FACEP
In patients with advanced cancer, the combination of disease progression over time, as well as habituation to chronic opioids, often leads to the need to increase opioid dosing over the course of illn

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