Critical Care Alert , Critical Care , Cardiology , EMS , Prehospital Care

Critical Care Alert: INCEPTION Trial

3/7/2023 Gabriel Colon, MD , Brian Sumner, MD , Evan McMurray, MD

The use of extracorporeal membrane oxygenation - ECMO - as an adjunct to CPR following out-of-hospital cardiac arrest has gained a lot of attention. The INCEPTION Trial takes a closer look at the evid

Critical Care , Critical Care Alert , Cardiology

Critical Care Alert: Epinephrine v. Norepinephrine in Cardiac Arrest Patients with Post-Resuscitation Shock

5/14/2022 Brendan Innes, MD , Brian Sumner, MD , Taylor Miller, MD

Post-resuscitation shock occurs in 50-70% of patients after out-of-hospital cardiac arrest, and this study provides evidence that norepinephrine is likely a preferable vasopressor to epinephrine in po

Deep Dive in CritCare , Critical Care

Deep Dive into the Evidence: Thrombolysis in Cardiac Arrest from PE

1/19/2022 Margarita Popova, MD , Jordan Feltes, MD , Yasir Hussein, MD , David Yamane, MD , Brian Sumner, MD

Few patients who suffer cardiac arrest from massive pulmonary embolism will survive to hospital discharge. From the evidence available, there is no clear mortality or functional outcome benefit to any

Critical Care , Critical Care Alert

Critical Care Alert: Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest

10/17/2021 Evan McMurray, MD , Erik Sherman, MD , Brian Sumner, MD

One study showed short-term benefit to using vasopressin and methylprednisolone in patients who experience in-hospital cardiac arrest. But study limitations mean further examination is needed before a

Deep Dive in CritCare , Critical Care

Deep Dive into the Evidence: Anaphylaxis

10/5/2021 Ying Ku , Megan Hoffer, DO , Brian Sumner, MD

Anaphylaxis is a severe life-threatening acute systemic type 1 hypersensitivity reaction. This IgE-mediated reaction leads to varying degrees of mast-cell degranulation, histamine release and varying

Critical Care , Critical Care Alert

Critical Care Alert: Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock

10/4/2021 Evan McMurray, MD , Erik Sherman, MD , Brian Sumner, MD

Managing critically ill patients with cardiogenic shock often includes a decision between two inotropes: dobutamine and milrinone. Is there evidence to inform that choice?

Critical Care , Critical Care Alert

Critical Care Alert: High-Dose Nitroglycerin Bolus for Sympathetic Crashing Acute Pulmonary Edema

10/4/2021 Michael Franczak, MD , Daniel Freeman, MD , Brian Sumner, MD

What's the feasibility and safety of giving a high-dose nitroglycerin bolus for sympathetic crashing acute pulmonary edema?

Critical Care , Deep Dive in CritCare , Cardiology

Targeted Temperature Management: Deep Dive Into the Evidence

8/10/2021 Ryan Lee, MD , Dustin Slagle, MD , Mustafa Rasheed, MD , Marshall Howell IV, MD , Javed Osmani , Elizabeth Avakoff, DO, MPH , Brian Sumner, MD

This EMRA Critical Care Committee Deep Dive will review the current available literature on targeted temperature management for cardiac arrest.

Critical Care , Critical Care Alert , Cardiology

Critical Care Alert: Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2 Trial)

8/2/2021 Mustafa Rasheed, MD , Marshall Howell IV, MD , Brian Sumner, MD

Evidence surrounding the benefits of post-arrest hypothermia has been conflicting, but it continues to be the standard of care per international guidelines. The TTM2 Trial adds to the data.

Critical Care , Critical Care Alert , Sepsis

Critical Care Alert: Fluid Resuscitation in Sepsis Induced Hypotension

8/2/2021 Erik Sherman, MD , Brian Sumner, MD

Early fluid resuscitation has been proven to be a fundamental component in improving survival for patients with severe sepsis or septic shock. But what happens when a patient has cirrhosis?