Critical Care , Critical Care Alert

Critical Care Alert: Role of N-Acetylcysteine in Non-acetaminophen-related Acute Liver Failure

4/5/2021 Jonathan Pickos, DO , Brian Sumner, MD

Non-acetaminophen-related causes of acute liver failure are inevitably going to present in the emergency department, and acknowledging that NAC likely has a place in the care of these patients is impo

Critical Care , Critical Care Alert , COVID-19

Critical Care Alert: Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure (The HOT-ICU Trial)

3/22/2021 Nicholas Huth , Jonathan Pickos, DO , Brian Sumner, MD

The ideal oxygenation goal in patients with acute respiratory failure in the ICU remains unclear. The HOT ICU trial seeks to provide insight.

Critical Care , Critical Care Alert , COVID-19

Critical Care Alert: Interleukin-6 Antagonists in Critically Ill Patients with COVID-19

3/18/2021 Oswald Reid, Jr., MD , Brian Sumner, MD

While much is still left to be known about COVID-19, research has supported the theory that an excessive host inflammatory response is responsible for much of the morbidity and mortality seen by the d

Critical Care , Critical Care Alert , COVID-19

Critical Care Alert: Tocilizumab in Patients Admitted to Hospital with COVID-19 (RECOVERY)

3/18/2021 Taylor Miller, MD , Brian Sumner, MD

Originally designed for use in rheumatoid arthritis, tocilizumab is being considered as a potential therapeutic agent to treat COVID-19.

Critical Care , Critical Care Alert , Sepsis

Critical Care Alert: Effect of Vitamin C, Thiamine and Hydrocortisone on Ventilator- and Vasopressor-Free Days in patients with sepsis - The VICTAS Randomized Clinical Trial

3/15/2021 Brian Sumner, MD

Does treatment with vitamin C, thiamine, and hydrocortisone lead to an increase in the number of days alive and free of mechanical ventilation and vasopressor use? The latest EMRA Critical Care Alert

Critical Care , Critical Care Alert , Cardiology , Sepsis

Critical Care Alerts: Effect of Ultra-Short-Acting Beta-blockers on Mortality in Patients with Persistent Tachycardia Despite Initial Fluid Resuscitation: A Systematic Review and Meta-Analysis

3/3/2021 Nicholas Huth , Jonathan Pickos, DO , Brian Sumner, MD

The latest EMRA Critical Care Alert examines a study that questions whether ultra-short-acting beta-blockers, such as esmolol and landiolol, reduced 28-day mortality in septic patients with persistent

CCA - Peripheral IV for Vasopressors.jpg

Critical Care , Critical Care Alert , Shock

Critical Care Alert: 2 Studies Shed Light on Efficacy, Effects of Peripheral IVs for Vasopressors

2/8/2021 Jonathan Pickos, DO , Brian Sumner, MD

Two recent papers offer insight into the use of peripheral IVs to administer vasopressors. Will these studies change your practice for critically ill patients in the emergency department?

Critical Care , Critical Care Alert , Shock

Critical Care Alert: Fluid Overload and Mortality in Adult Critical Care Patients

11/30/2020 Brian Sumner, MD , Sean M. Hickey, MD

Fluid overload has not been clearly defined in the critical care arena. In situations where patients have renal, cardiac, and pulmonary dysfunction, commonly seen in the ICU, large volume fluid therap

Critical Care , Pulmonary , COVID-19 , Deep Dive in CritCare

Corticosteroid Use in COVID-19 Respiratory Failure: Deep Dive into the Evidence

11/30/2020 Taylor Miller, MD , Brian Sumner, MD , Oswald Reid, Jr., MD , Sean M. Hickey, MD

The role of corticosteroids in severe infections, sepsis and ARDS has been a constantly evolving discussion and remains controversial. The recent APROCCHSs, ADRENAL and DEXA-ARDS along with other prio

Critical Care , Pulmonary , Airway , Deep Dive in CritCare

ARDS: Deep Dive into the Evidence

11/16/2020 Jonathan Pickos, DO , Brian Sumner, MD , Michael Franczak, MD , Melissa Villars, MD, MPH , Mina Ghobrial, MD , Sean M. Hickey, MD

Acute Respiratory Distress Syndrome (ARDS) is a life-threatening form of respiratory failure characterized by massive inflammation leading to pulmonary edema, decruitment of alveoli, and hypoxemia. De