Browsing: Critical Care Alert

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Critical Care , Critical Care Alert

Critical Care Alert: Targeted Temperature Management for Cardiac Arrest with Non-shockable Rhythm - The HYPERION Trial

12/19/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
Moderate therapeutic hypothermia could be another tool in treating cardiac arrest patients. But how much should a patient be cooled? The HYPERION Trial doesn't resolve that debate.
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Critical Care , Critical Care Alert

Critical Care Alert: CRASH-3 Review of TXA for TBI

12/16/2019 Ryan Lee, MD , Raymond Green, DO, FACS , Michael Perza, PharmD, BCPS
Released in October 2019, CRASH-3 is the latest trial exploring the benefits of tranexamic acid, this time in traumatic brain injury. The bottom line: TXA hasn't been shown to reduce mortality.
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Critical Care , Critical Care Alert

Critical Care Alert: Reviewing the Evidence for SEP-1

10/9/2019 Omid Manoochehri, MD , Sean M. Hickey, MD
The SEP-1 core measure instituted by CMS has been hotly debated. A new review of literature shows a lack of high-quality evidence to back up the specificity required in the sepsis bundle.
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Critical Care , Critical Care Alert

Critical Care Alert: The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS)

8/12/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
Fluid resuscitation guidelines for severe sepsis and septic shock presently address only the initial phase of resuscitation. The RIFTS trial examines the efficacy of a restrictive IV fluid resuscitati
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Critical Care , Critical Care Alert

Critical Care Alert: Re-evaluation of Systemic Early Neuromuscular Blockade: The ROSE Trial

7/16/2019 Jonathan Pickos, DO , Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
Does early neuromuscular blockade accompanied by heavy sedation in ARDS cases improve all-cause in-hospital mortality rates? The ROSE trial investigates.
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Critical Care , Critical Care Alert

Critical Care Alert: Measuring Lactate vs. Capillary Refill in Guiding Resuscitation in Shock: Is there a difference?

6/11/2019 Bryan Beattie, MD , Sean M. Hickey, MD
When trying to resuscitate patients with septic shock, which offers better guidance for intervention: measuring capillary refill or trending lactate levels? The Andromeda SHOCK trial studied patients
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Critical Care , Critical Care Alert

Critical Care Alert: Closed Chest Compressions in Traumatic Cardiac Arrest

5/18/2019 Sean M. Hickey, MD , Bryan Beattie, MD
The study authors sought to examine the effect of closed chest compressions on cardiac arrest due to hemorrhagic shock versus whole blood resuscitation.
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Critical Care , Critical Care Alert

Critical Care Alert: Bag-Mask Ventilation During Tracheal Intubation of Critically Ill Adults

5/17/2019 Sean M. Hickey, MD , Yanika Wolfe, MD , Meghan Gorski, DO
Does the application of positive pressure ventilation by bag valve mask during tracheal intubation improve outcomes in critically ill patients?
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Critical Care , Critical Care Alert

Critical Care Alert: Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER): A Randomized Trial

5/17/2019 Jonathan Pickos, DO , Sean M. Hickey, MD
The study authors sought to examine if early norepinephrine administration in patients diagnosed with septic shock improved shock control by 6 hours compared with standard care.
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Critical Care , Critical Care Alert

Critical Care Alert: Coronary Angiography after Cardiac Arrest without ST-Segment Elevation

5/17/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
This study examines whether immediate coronary angiography in the setting of ROSC without STEMI changes on ECG following out of hospital cardiac arrest confers superiority in 90 day mortality compared