Browsing: Critical Care Alert

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Critical Care , Critical Care Alert

Critical Care Alert: Targeted Temperature Management for Cardiac Arrest with Non-shockable Rhythm - The HYPERION Trial

12/19/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
Moderate therapeutic hypothermia could be another tool in treating cardiac arrest patients. But how much should a patient be cooled? The HYPERION Trial doesn't resolve that debate.
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Critical Care , Critical Care Alert

Critical Care Alert: CRASH-3 Review of TXA for TBI

12/16/2019 Ryan Lee, MD , Raymond Green, DO, FACS , Michael Perza, PharmD, BCPS
Released in October 2019, CRASH-3 is the latest trial exploring the benefits of tranexamic acid, this time in traumatic brain injury. The bottom line: TXA hasn't been shown to reduce mortality.
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Critical Care , Critical Care Alert

Critical Care Alert: Reviewing the Evidence for SEP-1

10/9/2019 Omid Manoochehri, MD , Sean M. Hickey, MD
The SEP-1 core measure instituted by CMS has been hotly debated. A new review of literature shows a lack of high-quality evidence to back up the specificity required in the sepsis bundle.
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Critical Care , Critical Care Alert

Critical Care Alert: The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS)

8/12/2019 Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
Fluid resuscitation guidelines for severe sepsis and septic shock presently address only the initial phase of resuscitation. The RIFTS trial examines the efficacy of a restrictive IV fluid resuscitati
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Critical Care , Critical Care Alert

Critical Care Alert: Re-evaluation of Systemic Early Neuromuscular Blockade: The ROSE Trial

7/16/2019 Jonathan Pickos, DO , Joshua Novy, MD, MBA, MS , Sean M. Hickey, MD
Does early neuromuscular blockade accompanied by heavy sedation in ARDS cases improve all-cause in-hospital mortality rates? The ROSE trial investigates.
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Critical Care , Critical Care Alert

Critical Care Alert: Measuring Lactate vs. Capillary Refill in Guiding Resuscitation in Shock: Is there a difference?

6/11/2019 Bryan Beattie, MD , Sean M. Hickey, MD
When trying to resuscitate patients with septic shock, which offers better guidance for intervention: measuring capillary refill or trending lactate levels? The Andromeda SHOCK trial studied patients
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Critical Care , Critical Care Alert

Critical Care Alert: Closed Chest Compressions in Traumatic Cardiac Arrest

5/18/2019 Sean M. Hickey, MD , Bryan Beattie, MD
The study authors sought to examine the effect of closed chest compressions on cardiac arrest due to hemorrhagic shock versus whole blood resuscitation.
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Critical Care , Critical Care Alert

Critical Care Alert: Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER): A Randomized Trial

5/17/2019 Jonathan Pickos, DO , Sean M. Hickey, MD
The study authors sought to examine if early norepinephrine administration in patients diagnosed with septic shock improved shock control by 6 hours compared with standard care.
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Critical Care , Critical Care Alert

Critical Care Alert: Crystalloids vs Colloids for Fluid Resuscitation in the Intensive Care Unit: A Systematic Review and Meta-analysis

5/17/2019 Omid Manoochehri, MD , Sean M. Hickey, MD
Surviving Sepsis Guidelines recommend crystalloids for initial fluid resuscitation then switching to albumin when crystalloids are insufficient. There is debate regarding using colloid as an initial r
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Critical Care , Critical Care Alert

Critical Care Alert: Bag-Mask Ventilation During Tracheal Intubation of Critically Ill Adults

5/17/2019 Sean M. Hickey, MD , Yanika Wolfe, MD , Meghan Gorski, DO
Does the application of positive pressure ventilation by bag valve mask during tracheal intubation improve outcomes in critically ill patients?